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Monoclonal Antibodies: How to Get Them, Plus a New Version


Regeneron/Ronapreve

Call 211 (in the US)

I've heard anecdotes from people who had a hard time getting an appointment for monoclonal antibodies. A city councilor here in Indianapolis recently had to be persistent and get a friend's doctor to intervene to get an appointment an hour's drive away. The news station he talked to advises readers to call 211 (in the US) to find the nearest facility that can treat you. If you're in Florida, you can just go to a Regeneron center. In Europe, it's called Ronapreve and different conditions apply for receiving treatment.

Monoclonal antibodies are for COVID-positive patients with mild to moderate symptoms who are at high risk of progression of the illness. They need to be administered within ten days of onset of symptoms. They can also be administered to people who are at high risk of catching COVID. Again--different conditions might apply outside the US.

Efficacy Against Omicron?

Regeneron says its monoclonal antibodies have "diminished potency against Omicron, [but] they are active against Delta, which currently is the most prevalent variant in the US." 

Evusheld

Evusheld is a new monoclonal antibody for prevention of COVID in immunocompromised patients or people who have a history of severe adverse reactions to COVID vaccines or their ingredients. The FDA has given it Emergency Use Authorization. Note that there were significantly higher rates of cardiovascular adverse events (e.g., heart attacks and heart failure) compared to placebo in the clinical trial. It has efficacy against the Omicron variant (see this also).

Contact your health care provider for more information.

Photo from Pexels.

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